The Role Of The Brain In Addiction

Technology has its mighty hand over every field in the world now. And since the base of technology is science, so how could medical sector not undergo changes! Neuroscience has always been an area of immense complexities and curiosities. Advances in this sector has allowed doctors to dig deeper into the brain and even study minutest of changes that happen due to substance intake.

When we talk about addiction as a brain disease, the reward system of the brain plays a very important role.

Physiologically, limbic system is the brain’s reward system. Mesolimbic and mesocortical pathways (Mid-brain) have our cognitive control and functions which would be both reward related and aversion related. Reward related functions are always stronger and more motivating than aversion, hence drug abuse behavior is stronger in addicts. The reward system connects certain structures in such a way that they generate the feeling of pleasure for certain behaviors or stimulus given to the body. In day-to-day life, it is activated by healthy, life-sustaining activities like eating and socializing. But ‘Drug Abuse’ is another behavior that generates euphoria, which is enjoyed by the mind. And human nature is to repeat those actions that give us some definite satisfaction. The limbic system does more than just giving a reward response. For any behavior to be reinforced, it has to be first registered as pleasant to the mind and body. Limbic system in the brain recognizes our positive and negative emotions, which very well explains, how our body and mind get dependent on any psychoactive mood altering substance.

However, with recent developments, neurobiology has been able to study how addiction is related to the brain. Researchers and scientists studied the brain’s reaction to different substances and discovered that drug abuse actually alters the chemical makeup of the brain, which is what causes addiction and they named it as a ‘Brain Disease.’

Since the brain is placed as the epicenter of human activity, it is the initiation point of every phenomenon that occurs. Whatever we feel, experience or think, all is first registered by the brain and within lesser than nanoseconds, it commands us to act. It communicates through neurons, neurotransmitters, receptors and transporters. Yes, it is very complicated and sounds mystical too (specially to people like me who have not studied biology after high school)

How do Drugs Affect the Brain?
Psychoactive substances interrupt with the communication systems of the brain. They interfere with the way a message is transmitted and sent to its defined destination. No matter how much people say that cannabis would not be called a drug, it is a plant, but the reality remains unchanged, which is, that everything has certain chemical composition. For example, Heroin and Marijuana’s chemical structure are like copies of a natural neurotransmitter. Amphetamines mimic catecholamine neurotransmitters, causing general physiological changes which prepare the body for physical activity and fight-or-flight response. So, the moment the body is intoxicated with a drug containing amphetamines or its derivatives, it starts reacting in unnatural ways by raising blood pressure, increased alertness resulting in sleeplessness, blood glucose levels. They can easily activate neurons, giving various directions to the body to react in a different way, than would a natural neurotransmitter would! Cocaine can make a person delirious, because it releases natural neurotransmitters in bulk and blocks the natural recycling process of neurotransmitters by the brain. Amphetamine causes drug tolerance very quickly and rapidly too.

Chronic addictive drug use causes alterations in the process by which information from a gene is used to synthesize a gene product- RNA or Protein. Nigrostriatal Pathway is a dopaminergic pathway that plays an extensive and unavoidable role in addiction. It comprises of Transcription Factor, which is a protein that controls what all information has to go from the DNA to the messenger RNA. Psychoactive substances block, many of the neural and behavioral alterations that are to be taken to the RNA. Altered dopamine transmission is the first thing that comes to notice in cases of drug abuse.

These have been many studies extensively done by medical science researchers on addiction. There is a wide range of chemicals that people use to reach a euphoric state. But the gist of it all is, that they play with the normal functioning of brain by altering the natural chemicals that ought to be there.

How Does the Reward System Work?
Whenever a person happens to do something that takes him to a different state of mind for a while, like reaching the oomph point in a sexually pleasurable activity, treating the taste buds with a new and a very different flavor or winning an excessive amount of money or any other valuable resource that he could use to be really rich, the brain takes it all in the same way. It activates the same gland and releases the same chemical Dopamine, which functions as a neurotransmitter, in all scenarios that seem to be pleasurable or exciting. Similarly, whenever the body receives an antibody that becomes too exciting for it like any drug, chemical or alcohol, the body releases certain amount of dopamine or cuts down its level. It is a problematic scenario is there is too much or too little of dopamine released by the brain. Drugs are addictive because they release up-to 10 times more dopamine than a natural neurotransmitter can! But when the body gets tolerant to the same drug and its amount, it can even cut down its normal release of dopamine!

How to Use the I Ching – Basic Three Coin Method

To use the I Ching, all you need is a copy of the I Ching and three coins that have a heads and a tails side. You will also need a scrap of paper and a writing utensil. Start by holding the coins in your hand, and think of a question you would like answered. When you have a clear idea of the question you would like to ask, throw the coins. Take a look at the results. Each head is worth 3 and each tails is worth 2. So add up the value. For example, suppose you throw the coins and the coins fall as two heads and one tail. That means the total would be 8. 3 + 3 + 2 = 8. So for the first line, you would record an 8. Repeat this process five more times, writing the numerical values in a vertical sequence from bottom to top. Once you have these 6 numerical values, you are ready to begin building your hexagram.

To build a hexagram, you’re going to simply write a broken line for each even value, and a solid line for each odd value. Once you have 6 lines, you have made a hexagram. When your hexagram is formed, you must now look it up in your copy of the I Ching. Usually on the very last page of your I Ching there will be a chart that makes looking up the hexagram easy. When you find your hexagram, read the chapter of the I Ching that corresponds to the hexagram.

Take a look at your hexagram. Do you have any sixes or nines? If so you will need to read the text under the line that is either six or nine. Usually this will be written in your I Ching as first line, second line, etc., or in some cases it will be described as first six, second nine, and so on. These are known as the changing lines. The text that is in this section pertains specifically to you and your question. Now you will make a second hexagram.

For the second hexagram you will need to change all of the lines with a six to nine, and all the lines with a nine to a six. Leave the rest of the lines the same. Then look up the resulting hexagram in the same way you did the first time, including the six and nine lines. Finally, after you have done all this, you will then ‘check your work’ using the rtcm (retrospective three coin method). This is a method that I learned about by reading a book by Carol Anthony, who is a leading writer on the subject of the I Ching. To use this method, simply form a theory about what you think the I Ching is trying to tell you. When you have a theory, hold it in your mind and toss the coins. If you get three heads, it means yes. Three tails is no. Two heads is yes, but… and two tails is no, but… keep doing this until you get a clear idea of what the I Ching is telling you. When you ask it if a particular interpretation of the reading is correct, toss the coins, and they are all three heads up, you will know that you have hit on a correct interpretation.

Cosmetic Surgery is Now a Thriving Sector

Cosmetic Surgery is not a New Term

Cosmetic surgery needs no introduction in today’s world where more of us are becoming more conscious to look beautiful. Indeed, you cannot say it is only the celebrities who want to look beautiful to stay in the glamour business. Common people like you and me also want to look equally attractive like a top heroine.

Defining This Type of Surgery

It is basically reconstructing a defective part of your body. For example, you have a flat thick nose. You are not happy with it and want a symmetrical nose. So, through cosmetic surgery you can enhance your nose to make it look right. Also, through this type of surgery, the surgeons will reshape your nose in such a way it perfectly balances with the face. Again, there are many people who have a nose that obstructs airway. A cosmetic surgeon can easily correct obstructed airway for proper breathing.

Worldwide Boom of Cosmetic Surgery

You cannot trace the time since people from all across the globe started looking for experienced surgeons to do different types of plastic surgery. There are a good number of hospitals and private health clinics that have experienced surgeons and state of the art facilities to give the best possible attention and care to patients trying to look attractive and younger. It is not only the celebrities who are spending large amount of money to enhance their looks or correct a birthmark. There are teenagers, executives and even housewives who are flocking at this health centers in large numbers to know more about cosmetic surgery, how much it cost and the result post-surgery. This type of surgical procedure is minimally invasive. The centers have some exceptionally talented cosmetic surgeons with years of experience. The surgeons do their best to make people look beautiful and enhance their look and confidence through minimally invasive procedures.

Low Fees and Surgery Costs

These days many health clinics perform cosmetic surgeries at a low-cost. In minimally invasive surgery or laparoscopy, the surgeon makes a small hole in the abdomen. It is also less painful and the patient heals quickly.

Types of Cosmetic Surgery

Nose reshaping: People with a flat nose, protruding nostrils, nose with narrow air passage go for this type of surgery. Also known as rhinoplasty, it helps to correct the nose shape as well as clear the airway to make breathing a hassle-free task.

Facial surgery: The doctors boost the aesthetic aspects of your face, mouth, teeth and jaws through skin, muscle, bones and cartilage grafting.

Arm lifting: Brachioplasty is a surgical procedure to correct your upper arms. Many people have excess fat on their upper arms and they are unhappy with it. They can go to a cosmetic surgeon to remove the excess fat and skin from their underarms.

Breast enlargement and reduction: If you have a small breast, you can enlarge it through minimally invasive surgical procedure. Again, if someone has large breasts they can cut the same through cosmetic surgery to boost their look and confidence.

Eyelid surgery: Surgeons removes fat and excess skin from the upper eyelids to improve eyesight.

Liposuction: In spite of dieting and regular exercise, the excess fat in your body does not burn. Liposuction helps to remove fat deposits.

Tummy Tucking: Doctors make small incisions in the abdomen to remove excess skin and fat. Muscles are then tightened to give a younger look.